site stats

Human il-2 uniprot

WebIL-2 signals through the IL-2 receptor (IL-2R), a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL-4) and interleukin 7 (IL-7). The … WebSep 17, 2024 · The present invention relates to a pharmaceutical composition for enhancing immunity, and was arrived at by discovering that oligopeptide AQTGTGKT and an analog thereof have the effect of appropriately modulating immune activity in the body, such as by suppressing excessive immune response while enhancing immune activity for defending …

Human IL-2 ELISpot Pair - Assay Genie

WebRecombinant human IL-2 is a non-glycosylated protein containing 134 amino acids. Recombinant human IL-2 has a Ser substitute for Cysteine at position 126. Reconstitute using sterile 10 mM HCl at 0.1 mg/mL and … WebA novel interleukin-2-based fusion molecule, HCW9302, differentially promotes regulatory T cell expansion to treat atherosclerosis in mice. View PDF In Frontiers in Immunology on … flights to havasu falls arizona https://boatshields.com

UniProt

WebApr 4, 2024 · Tat. tat. HIV-1 Tat upregulates the expression of interleukin 15 (IL15) gene in mammary epithelial cells. PubMed. capsid. gag. Unactivated memory CD4+ T cells infected by HIV-1 in the presence of IL-2 and IL-15 alone or IL-6/IL-7/TNF-alpha combination, upregulate granzyme B and HIV-1 CA production. WebMay 23, 2024 · Cryo-EM structures of 11-2 F / MTA-bound human PRMT5/MEP50 complex and its apo form resolved at 3.1 and 3.2 Å respectively show that 11-2 F in the catalytic pocket shifts the cofactor-binding pocket away by ~2.0 Å, contributing to positive cooperativity. ... 2.1.1.320: UniProt & NIH Common Fund Data Resources: Find proteins … WebUseful information about the gene from Entrez. The protein encoded by this gene is closely related to Il13RA1, a subuint of the interleukin 13 receptor complex. This p rotein binds … cheryle kempton

WO2024043269A1 - Pharmaceutical composition for modulating …

Category:(130-097-745) Human IL-2 IS, premium grade - CiteAb

Tags:Human il-2 uniprot

Human il-2 uniprot

Human IL-2 Recombinant Protein (PHC0021)

WebRecombinant Mouse IL-2 (Catalog # 402-ML) stimulates cell proliferation of the CTLL-2 mouse cytotoxic T cell line. The ED 50 for this effect is 0.1-0.4 ng/mL. SDS-PAGE View Larger. 1 μg/lane of Recombinant Mouse IL-2 was resolved with SDS-PAGE under reducing (R) conditions and visualized by silver staining, showing a band (s) at 19 kDa. WebJul 2, 2002 · Total Structure Weight: 15.63 kDa Atom Count: 1,055 Modelled Residue Count: 122 Deposited Residue Count: 133 Unique protein chains: 1 Display Files Download …

Human il-2 uniprot

Did you know?

WebHuman, recombinant IL-2 has the same biological activity in vitro as compared to human, natural IL-2 (15, 1–4). Interleukin-2 (IL-2, also known as T-Cell Growth Factor, TCGF) is … WebLess than 0.01 ng endotoxin/1 μg hIL-2. Activity. The bioactivity of recombinant hIL-2 was determined in a CTLL-2 cell proliferation assay. The ED 50 of each lot is between 0.1 - …

WebInterleukin 2 (IL-2) is an immuno-modulatory cytokine that is important for the proliferation of activated T cells, differentiation of B cells, natural killer cells, monocytes and … WebRecombinant human Interleukin-2 (IL-2) is expressed in human HEK 293 cells with a calculated molecular mass of 15 kDa. This protein is manufactured in human cells, ... Endotoxin: 1.00 EU/µg IL-2 (LAL) Uniprot: P60568 Precautions and Disclaimer For R&D use only. Not for drug, household, or other uses. Please consult the Safety Data Sheet for

WebIL-2, Human Interleukin-2 (IL-2) is a Oglycosylated, four α-helix bundle cytokine that has potent stimulatory activity for antigen-activated T cells. It is expressed by CD4+ and CD8+ T cells, γδ T cells, B cells, dendritic cells, and eosinophils. WebDescription. Interleukin-2 Human Recombinant produced in E.Coli is a single, non-glycosylated, Polypeptide chain containing 133 amino acids fragment (21-153) having a …

WebHuman IL-2 is synthesized as a 153-amino-acid precursor polypeptide and is then processed to mature IL-2. Mature human IL-2 is a 15.5 kDa four-alpha-helix bundle glycoprotein that consists of 133 amino acids.

Web16183 Ensembl ENSG00000109471 ENSMUSG00000027720 UniProt P60568 P04351 RefSeq (mRNA) NM_000586 NM_008366 RefSeq (protein) NP_000577 NP_032392 Location (UCSC) Chr 4: 122.45 – 122.46 Mb Chr 3: 37.17 – 37.18 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Interleukin-2 (IL-2) is an interleukin, a … cheryle keck illnessWebInterleukin-2, T-cell growth factor, IL2_HUMAN. UniProt Code History. P60568. Gene. IL2, IL-2, TCGF, lymphokine. Bioactivity. The ED50 as determined by the dose-dependent stimulation of murine CTLL-2 cells is ≤ 0.1 ng/ml, corresponding to a specific activity of ≥ 1 x 107 units/mg. Purification Method. SDS-PAGE & HPLC >= 98% cheryle james-wallaceWebInterleukin-2 (IL-2) is an α-helical cytokine belonging to T-helper cell type 1. It has a molecular weight of 15kDa. The IL2 gene is mapped to human chromosome 4q27. IL-2 … flights to haverford