WebThe dibenzocyclooctyne group (DBCO) is thermally stable with high specific reactivity toward azide group through strain-promoted click reaction in the absence of a … WebThe dibenzocyclooctyne group (DBCO) is thermally stable with high specific reactivity toward azide group through strain-promoted click reaction in the absence of a catalyst. Excellent biocompatibility – strain-promoted click reaction occurs rapidly under mild buffer conditions with no need of accessory toxic copper catalyst.

Dibenzocyclooctyne-PEG4- N -hydroxysuccinimidyl ester

WebJul 26, 2016 · After UV irradiation, the dibenzocyclooctyne group was quantitatively released, and intramolecularly reacted with alternative azide end group to produce the … WebSep 27, 2024 · Recently, microRNAs (miRNA) captured the interest as novel diagnostic and prognostic biomarkers, with their potential for early indication of numerous pathologies. Since miRNA is a short, non-coding RNA sequence, the sensitivity and selectivity of their detection remain a cornerstone of scientific research. As such, methods based on … chrysler port arthur

N-Hydroxysuccinimide Ester - an overview ScienceDirect Topics

WebThe dibenzocyclooctyne group (DBCO) allows Copper-free Click Chemistry to be done with live cells, whole organisms, and non-living samples. DBCO groups will preferentially … WebDec 23, 2024 · The approach consisted of two steps: (i) the carboxylic acid group of the bipyridine ligand in complex Ir-I was first attached to an amine functionalized dibenzocyclooctyne group via amide formation to generate complex Ir-II; and (ii) the alkyne bond of dibenzocyclooctyne in complex Ir-II underwent a subsequent strain … Webfunctional group. amine. storage temp. −20°C. SMILES string. NCCC(N1CC2=C(C=CC=C2)C#CC3=C1C=CC=C3)=O. ... This dibenzocyclooctyne will react with azide functionalized compounds or … chrysler poughkeepsie ny